Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1393299 | European Journal of Medicinal Chemistry | 2009 | 8 Pages |
Abstract
A series of novel dispiropyrrolidine derivatives have been synthesized through 1,3-dipolar cycloaddition reaction of azomethine ylide generated from sarcosin and di/tri ketone with the dipolarophile (E)-2-arylidine-1-keto-carbazoles.The cycloadducts ketocarbazalo spiro N-methyl pyrrolidines showed the most interesting antimicrobial activity at lower concentration.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Govindasami Periyasami, Raghavachary Raghunathan, Gangadharan Surendiran, Narayanasamy Mathivanan,