Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1393381 | European Journal of Medicinal Chemistry | 2008 | 4 Pages |
Abstract
A successful synthesis of fukiic acid is described in 7% overall yield (6 steps from veratraldehyde). rac-Fukiic acid was found to be a potent inhibitor of HIV-1 integrase but did not reveal antiviral activity in the MT-4 cells assay.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Clémence Queffélec, Fabrice Bailly, Gladys Mbemba, Jean-François Mouscadet, Zeger Debyser, Myriam Witvrouw, Philippe Cotelle,