4-Thiazolidinone – A biologically active scaffold

The broad and potent activity of 4-thiazolidinones has established it as one of the biologically important scaffolds. This article is an effort to highlight the importance of the 4-thiazolidinones in the present context and promise they hold for the future.

Graphical abstractThe broad and potent activity of 4-thiazolidinones has established it as one of the biologically important scaffolds. The article has outlined the chemistry and biological activities of the 4-thiazolidinone scaffold. The synthetic methodologies indicate the simplicity, maneuverability and versatility, which offer the medicinal chemist a complete range of novel derivatives.Figure optionsDownload full-size imageDownload as PowerPoint slide