| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1393519 | European Journal of Medicinal Chemistry | 2007 | 5 Pages |
Abstract
A new quinazolone series has been designed, and synthesized by the anthranilic acid and different acid derivatives. Their structures have been elucidated on the basis of elemental analyses and spectral studies (IR, 1H NMR, FT-IR and FAB-MS). A preliminary radiolabelling study with technetium has shown a very good future prospect for further evaluation in vivo. The biological activities (antifungal, antibacterial as well as anticancerous) of the evaluated compounds are discussed in this article.
Graphical abstractSynthesis of 4-(3H)-quinazolone analogues.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Anjani K. Tiwari, Vinay Kumar Singh, Aruna Bajpai, Gauri Shukla, Sweta Singh, Anil K. Mishra,