| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1393531 | European Journal of Medicinal Chemistry | 2007 | 6 Pages |
Abstract
Synthesis and cytotoxic activity of a series of 4-methyl-1,2,3-selenadiazole-5-carboxylic acid amides on human fibrosarcoma HT-1080, mouse hepatoma MG-22A, and mouse fibroblasts 3T3 cell lines are described. The correlation between compound LD50 and 3T3 fibroblast cell line morphology was shown. In vivo evaluation of amides on mouse sarcoma S-180 confirms high antitumor activity (58–85%).
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Related Topics
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Authors
Pavel Arsenyan, Kira Rubina, Irina Shestakova, Ilona Domracheva,