Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoprotein

Article ID	Journal	Published Year	Pages	File Type
1393818	European Journal of Medicinal Chemistry	2016	20 Pages	PDF

Keywords

Mcl-1 Bcl-xL Protein–protein interaction Apoptosis Cancer

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoprotein

Authors

Maryanna E. Lanning, Wenbo Yu, Jeremy L. Yap, Jay Chauhan, Lijia Chen, Ellis Whiting, Lakshmi S. Pidugu, Tyler Atkinson, Hala Bailey, Willy Li, Braden M. Roth, Lauren Hynicka, Kirsty Chesko, Eric A. Toth, Paul Shapiro, Alexander D. Jr., Paul T. Wilder,