| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1394566 | European Journal of Medicinal Chemistry | 2011 | 5 Pages |
A new class of oxazolyl/thiazolylsulfonylmethyl pyrazoles (10–13) and isoxazoles (14, 15) were prepared from the synthetically vulnerable intermediate E-styrylsulfonylacetic acid methyl ester (1) and studied their antioxidant activity.
Graphical abstractA new class of oxazolyl/thiazolylsulfonylmethyl pyrazoles (10–13) and isoxazoles (14, 15) were prepared from the synthetically vulnerable intermediate E-styrylsulfonylacetic acid methyl ester (1) and studied their antioxidant activity.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► A new class of oxazolyl/thiazolylsulfonylmethyl pyrazoles and isoxazoles were prepared. ► The compound isoxazole in combination with oxazoline exhibited greater antioxidant activity. ► Presence of electron donating substituents on the aromatic ring enhances the activity.
