| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1394612 | European Journal of Medicinal Chemistry | 2011 | 14 Pages |
Abstract
⺠We prepared of LCAP with a terminal fragment of pyrimido[5,4-c]quinolone. ⺠The majority of compounds demonstrated high in vitro affinity for 5-HT1A receptor. ⺠We conducted X-ray analysis, two-dimensional NMR, conformational studies. ⺠We assessed conformational preferences of ligands in different environments.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis and structural investigation of some pyrimido[5,4-c]quinolin-4(3H)-one derivatives with a long-chain arylpiperazine moiety as potent 5-HT1A/2A and 5-HT7 receptor ligands](/preview/png/1394612.png "First Page Preview: Synthesis and structural investigation of some pyrimido[5,4-c]quinolin-4(3H)-one derivatives with a long-chain arylpiperazine moiety as potent 5-HT1A/2A and 5-HT7 receptor ligands")
Authors
Wieslawa Lewgowd, Andrzej J. Bojarski, Malgorzata Szczesio, Andrzej Olczak, Marek L. Glowka, Stefan Mordalski, Andrzej Stanczak,