Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1395045 | European Journal of Medicinal Chemistry | 2009 | 5 Pages |
Abstract
A series of C18-oxygenated derivatives of abietic acid were synthesized and evaluated for their cytotoxic, antimycotic, and antiviral activities. In general, the introduction of an aldehyde group at C18 did improve the resultant bioactivity, while the presence of an acid or alcohol led to less active compounds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Miguel A. González, Julieth Correa-Royero, Lee Agudelo, Ana Mesa, Liliana Betancur-Galvis,