| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1395072 | European Journal of Medicinal Chemistry | 2009 | 6 Pages |
Abstract
Novel 2-substituted isobutyric acid derivatives were synthesized and their hypolipidemic activity was evaluated in high cholesterol diet fed rat model. The amide 5a was found to decrease the levels of serum total cholesterol, LDL cholesterol and triglycerides in hyperlipidemic rats to a greater degree than the reference gemfibrozil.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gamal A. Idrees, Gamal El-Din A. Abuo-Rahma, Omar M. Aly, Mohamed F. Radwan,