| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1395074 | European Journal of Medicinal Chemistry | 2009 | 7 Pages |
Abstract
Novel mono- and diacylated spermines, readily obtained using isolable succinimidyl active esters of acidic retinoids for the selective acylation of free spermine or in situ activated acidic retinoids for acylating selectively protected spermine followed by deprotection, were shown to inhibit the ribozyme ribonuclease P more strongly than the parent retinoids.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
George Magoulas, Dionysios Papaioannou, Evangelia Papadimou, Denis Drainas,