| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1395191 | European Journal of Medicinal Chemistry | 2009 | 6 Pages |
Abstract
Fourteen new derivatives of the 2-azetidinone cholesterol absorption inhibitors have been synthesized, and three of them were enantiomerically pure. All the new compounds were evaluated for their activity to inhibit cholesterol absorption in rats, and most of them showed comparable effects in lowering the levels of total cholesterol in the serum.
Graphical abstractFourteen new derivatives of the 2-azetidinone cholesterol absorption inhibitors have been synthesized. All the new compounds were evaluated for their activity to inhibit cholesterol absorption in rats.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yubin Wang, Huibin Zhang, Wenlong Huang, Jing Kong, Jinpei Zhou, Beibei Zhang,