Article ID Journal Published Year Pages File Type
1395458 European Journal of Medicinal Chemistry 2007 7 Pages PDF
Abstract

A new series of oxazolidinones containing triazolyl group has been synthesized and tested for in vitro antibacterial activity by MIC determination against a panel of resistant and susceptible Gram-positive organisms. Most of the analogs in this series displayed activity superior to linezolid and vancomycin in vitro. Further, in vivo efficacies of the selected oxazolidinones were also disclosed herein.

Graphical abstractA new series of oxazolidinones containing triazolyl group has been synthesized and their in vitro antibacterial activity (MIC) was evaluated, furthermore, in vivo efficacies of the selected compounds were also disclosed herein.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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