Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1395458 | European Journal of Medicinal Chemistry | 2007 | 7 Pages |
Abstract
A new series of oxazolidinones containing triazolyl group has been synthesized and tested for in vitro antibacterial activity by MIC determination against a panel of resistant and susceptible Gram-positive organisms. Most of the analogs in this series displayed activity superior to linezolid and vancomycin in vitro. Further, in vivo efficacies of the selected oxazolidinones were also disclosed herein.
Graphical abstractA new series of oxazolidinones containing triazolyl group has been synthesized and their in vitro antibacterial activity (MIC) was evaluated, furthermore, in vivo efficacies of the selected compounds were also disclosed herein.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
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Authors
Houxing Fan, Gang Xu, Yilang Chen, Zhiteng Jiang, Shuhua Zhang, Yushe Yang, Ruyun Ji,