Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1395459 | European Journal of Medicinal Chemistry | 2007 | 7 Pages |
Abstract
A novel synthetic approach to N-aryl-4-(3-pyridyl)thiazol-2-amine and analogues using HMCM-41 and their in vitro ADP-induced platelet aggregation inhibitory activity on human blood platelets is described. Among the test compound, N-(2â²-flourophenyl)-4-(3-pyridyl)thiazol-2-amine (9e) was found to be the most potent, IC50Â =Â 4.84Â ÃÂ 10â7Â M.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Umadevi Bhoga,