| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1395695 | European Journal of Medicinal Chemistry | 2006 | 7 Pages |
Abstract
The synthesis and antimicrobial activity of new pyrrole derivatives structurally related to monodeoxypyoluteorin are described. The insertion of a keto or methylene spacer between the phenol group and the pyrroloyl moiety of brominated 2-(2′-hydroxybenzoyl)pyrroles leads to a decrease of the antibacterial activity.
Graphical abstractThe synthesis and antimicrobial activity of new pyrrole derivatives related to monodeoxypyoluteorin are described. The insertion of a keto or methylene spacer in the bond between phenol group and pyrroloyl moiety of brominated 2-(2′-hydroxybenzoyl)pyrroles leads to a decrease of the antibacterial activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Maria Valeria Raimondi, Stella Cascioferro, Domenico Schillaci, Salvatore Petruso,