Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1395742 | European Journal of Medicinal Chemistry | 2014 | 8 Pages |
•Amine linked bis- and tris-heterocycles were prepared from heteroaryl cinnamamides.•The compounds 11c and 12c exhibited excellent antibacterial activity while 12a and 12c displayed excellent antifungal activity.•The presence of electron withdrawing substituent on aromatic ring enhances the activity.
A series of amine linked bis- and tris-heterocycles were prepared from heteroaryl cinnamamides and tested for antimicrobial activity. The compounds 11c and 12c exhibited excellent antibacterial activity while 12a and 12c displayed excellent antifungal activity.
Graphical abstractA series of amine linked bis- and tris-heterocycles were prepared from heteroaryl cinnamamides and tested for antimicrobial activity. The compounds 11c and 12c exhibited excellent antibacterial activity while 12a and 12c displayed excellent antifungal activity.Figure optionsDownload full-size imageDownload as PowerPoint slide