| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1395744 | European Journal of Medicinal Chemistry | 2014 | 9 Pages |
Abstract
Compounds 3m and 14 were isolated as new potent antiprion compounds active against both yeast and mammalian prions. The IC50 in the mammalian cell-based assay was around 5 μM for 3m and 1.8 μM for 14.
Related Topics
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Organic Chemistry
Authors
Phuhai Nguyen, Nassima Oumata, Flavie Soubigou, Justine Evrard, Nathalie Desban, Pascale Lemoine, Serge Bouaziz, Marc Blondel, Cécile Voisset,