Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1395952 | European Journal of Medicinal Chemistry | 2012 | 8 Pages |
Abstract
⺠[Pt(L)Cl4] inhibits tumor, but not immune cell viability. ⺠[Pt(L)Cl4] inhibits cytokine and nitric oxide generation by immune cells. ⺠[Pt(L)Cl4] has tumoricidal and immunomodulatory, but not immunosuppressive effect. ⺠These features promote [Pt(L)Cl4] as a likely anticancer and immunomodulatory drug.
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Authors
Djordje MiljkoviÄ, Jelena M. PoljareviÄ, Filip PetkoviÄ, Jana Blaževski, Miljana MomÄiloviÄ, Ivana NikoliÄ, Tamara Saksida, Stanislava StoÅ¡iÄ-GrujiÄiÄ, Sanja GrguriÄ-Å ipka, Tibor J. Sabo,