| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1395979 | European Journal of Medicinal Chemistry | 2012 | 10 Pages |
Abstract
⺠Hydrazide INH and its analog PCH and 2,4-DHBAH interact with DNA via intercalation. ⺠All compounds showed good DNA binding as investigated by UV and voltammetric studies. ⺠Binding constant results from both techniques were in good agreement and showed stronger binding. ⺠Kb and n values of 2,4-DHBAH revealed its relatively stronger binding at stomach pH. ⺠All compounds have anti-oxidant potential; 2,4-DHBAH showed anti-bacterial activity.
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Authors
Nasima Arshad, Uzma Yunus, Shumaila Razzque, Maliha Khan, Samreen Saleem, Bushra Mirza, Naghmana Rashid,