Article ID Journal Published Year Pages File Type
1396172 European Journal of Medicinal Chemistry 2011 10 Pages PDF
Abstract
►We synthesized 22 compounds as potent NHE1 inhibitors. ►All the compounds were evaluated for NHE1 inhibitory activity screening. ►12 Compounds showed more potent NHE1 inhibitory activity than cariporide. ►3 Compounds were two orders of magnitude higher than that of cariporide. ►1 Compound had highlighted protective effect on cardiomyocytes.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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