Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1396172 | European Journal of Medicinal Chemistry | 2011 | 10 Pages |
Abstract
âºWe synthesized 22 compounds as potent NHE1 inhibitors. âºAll the compounds were evaluated for NHE1 inhibitory activity screening. âº12 Compounds showed more potent NHE1 inhibitory activity than cariporide. âº3 Compounds were two orders of magnitude higher than that of cariporide. âº1 Compound had highlighted protective effect on cardiomyocytes.
Related Topics
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Organic Chemistry
Authors
Lu Jin, Xiang-Min Jiang, Ping Du, Jing Xu, Guo-qing Gong, Qiu-juan Wang, Yun-gen Xu,