| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1396260 | European Journal of Medicinal Chemistry | 2010 | 6 Pages |
Abstract
A series of functionally substituted pyrazole compounds have been synthesized and evaluated in vitro for their antiproliferative effects on a panel of 60 cellular lines, according to the National Cancer Institute screening protocol. Three of the 12 tested compounds showed moderate antitumor activity, one of them being chosen for the 5-dose assay and presented logGI50 values up to −5.75.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
George Mihai Nitulescu, Constantin Draghici, Alexandru Vasile Missir,