| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1396275 | European Journal of Medicinal Chemistry | 2010 | 5 Pages |
Abstract
A series of 6-substitutedphenyl thiazolo-1,2,4-triazinones (8) were obtained by the initial reaction of 6-substituted arylmethyl-3-mercapto-1,2,4-triazin-5-ones (5) with substituted phenacyl bromides (6) and further followed by PPA cyclization. The structures of the newly synthesized compounds were confirmed by IR, 1H NMR, Mass and analytical data. Compounds 8a, 8e, 8f and 8h exhibited good antimicrobial activity.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mari Sithambaram Karthikeyan,