| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1396381 | European Journal of Medicinal Chemistry | 2010 | 6 Pages |
Abstract
Eleven shikonin glycosides were synthesized and evaluated for their antitumor activity in vitro. Some of them were found to exhibit cytotoxic activities against both drug sensitive cell lines (K562, MCF-7 and HL60) and their drug resistant cell sublines (K562/ADR, MCF-7/ADR and HL60/ADR).
Graphical abstractEleven shikonin glycosides were synthesized and evaluated for there antitumor activity in vitro. Some of them were found to exhibit cytotoxic activities against both drug-sensitive and drug-resistant cell lines.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yehua Su, Jiansheng Xie, Yanguang Wang, Xun Hu, Xianfu Lin,