Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1396449 | European Journal of Medicinal Chemistry | 2010 | 6 Pages |
Abstract
Novel 3,8-disubstituted-pyrimido[5,4-d]pyrimidines were synthesized and evaluated against Mycobacterium tuberculosis strain H37Rv. The new compounds showed activity against the bacilli that depends on the substituents present in N-3 and C-8.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ana H. Bacelar, M. Alice Carvalho, M. Fernanda Proença,