Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1396535 | European Journal of Medicinal Chemistry | 2010 | 4 Pages |
Abstract
A series of imidazo[1,2-a]pyrrolo[2,3-c]pyridines has been prepared and evaluated for their anti-BVDV activities in MDBK cells. From the synthesized analogues bearing modifications of the substituents at positions 2, 3, 7 and 8, compounds 10a, b, 16, 24, 25 and 26 exhibited significant anti-BVDV activities.
Graphical abstractThe synthesis and the structure–activity relationship of some imidazo[1,2-a]pyrrolo[3,2-c]pyridine derivatives as anti-BVDV agents is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jean-Michel Chezal, Jan Paeshuyse, Vincent Gaumet, Damien Canitrot, Aurélie Maisonial, Claire Lartigue, Alain Gueiffier, Emmanuel Moreau, Jean-Claude Teulade, Olivier Chavignon, Johan Neyts,