| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1396548 | European Polymer Journal | 2008 | 9 Pages |
Abstract
P(DMAEMA-g-EG) cationic hydrogel nanoparticles (CHNPs) were prepared by distillation–dispersion copolymerization of poly(ethylene glycol) methyl ether methacrylate (MPEGMA) and N,N-dimethylaminoethyl methacrylate (DMAEMA) using acetonitrile (AN) as dispersion medium. The results of FTIR spectra indicate that the composition of P(DMAEMA-g-EG) CHNPs is consistent with the designed structure. The TEM image shows that P(DMAEMA-g-EG) CHNPs are of spherical morphology before and after swelling. The investigations on the properties of P(DMAEMA-g-EG) CHNPs indicate that P(DMAEMA-g-EG) CHNPs have pH-, ionic strength- and thermo-sensitive characters. This type of P(DMAEMA-g-EG) CHNP is very promising as environment-sensitive drug carriers.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Liandong Deng, Yinglei Zhai, Xiaona Lin, Fengmin Jin, Xiaohua He, Anjie Dong,