Article ID Journal Published Year Pages File Type
1396591 European Journal of Medicinal Chemistry 2009 9 Pages PDF
Abstract

Several 4,5-bis(dialkylaminoalkyl)-substituted acridines have been prepared starting from acridine and their telomeric G-quadruplex stabilizing properties were evaluated using FRET melting and TRAP (Telomerase Repeat Amplification Protocol Assay) experiments.

Graphical abstractSome 4,5-bis(dialkylaminoalkyl)-substituted acridines have been prepared and their telomeric G-quadruplex stabilizing properties were evaluated.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , , , ,