Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1396591 | European Journal of Medicinal Chemistry | 2009 | 9 Pages |
Abstract
Several 4,5-bis(dialkylaminoalkyl)-substituted acridines have been prepared starting from acridine and their telomeric G-quadruplex stabilizing properties were evaluated using FRET melting and TRAP (Telomerase Repeat Amplification Protocol Assay) experiments.
Graphical abstractSome 4,5-bis(dialkylaminoalkyl)-substituted acridines have been prepared and their telomeric G-quadruplex stabilizing properties were evaluated.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marie Laronze-Cochard, Young-Min Kim, Bertrand Brassart, Jean-François Riou, Jean-Yves Laronze, Janos Sapi,