Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1396922 | European Journal of Medicinal Chemistry | 2008 | 5 Pages |
Abstract
A series of Schiff bases have been synthesized from dicarbaldehyde of benzocoumarin, in which the reactions were regioselective and the products existed in the keto-enamine form, in which the aromaticity of the relevant ring was disrupted. The compounds were evaluated in vitro for their antioxidant and in vivo for their antidyslipidemic activity for the first time. Compounds 3 and 7 possess significant lipid lowering and antioxidant activity.
Graphical abstractA series of keto-enamine Schiff bases have been synthesized and evaluated for antidyslipidemic and antioxidant activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Koneni V. Sashidhara, Jammikuntla N. Rosaiah, Gitika Bhatia, J.K. Saxena,