Article ID Journal Published Year Pages File Type
1396974 European Journal of Medicinal Chemistry 2007 8 Pages PDF
Abstract

A number of levofloxacin analogues carrying a 2-aryl-2-oxoethyl or a 2-aryl-2-oxyiminoethyl moiety attached to the piperazine ring at C-10 position have been prepared and evaluated as antibacterial agents against a series of Gram-positive and Gram-negative bacteria. Some of them exhibited significant inhibitory activity against Gram-positive bacteria.

Graphical abstractA number of levofloxacin analogues carrying a 2-aryl-2-oxoethyl or a 2-aryl-2-oxyiminoethyl moiety attached to the piperazine ring at C-10 position have been prepared and evaluated against a panel of Gram-positive and Gram-negative bacteria. Some of them exhibited significant inhibitory activity against Gram-positive bacteria.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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