| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1397033 | European Journal of Medicinal Chemistry | 2007 | 10 Pages |
Abstract
Aminoalkyl derivatives of diarylmethanes were prepared using Grignard, Friedel–Crafts arylation and aminohydrochloride chain formation reactions. These series of compounds were evaluated against Mycobacterium tuberculosis H37Rv and showed the activity in the range of 6.25–25 μg/mL. Effect of heteroaryl, anthracenyl and phenanthrene groups on diarylmethane pharmacophores for antitubercular activity is described.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gautam Panda, Maloy Kumar Parai, Sajal Kumar Das, Shagufta, Manish Sinha, Vinita Chaturvedi, Anil K. Srivastava, Y.S. Manju, Anil N. Gaikwad, Sudhir Sinha,