| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1397142 | European Journal of Medicinal Chemistry | 2006 | 5 Pages |
Abstract
The synthesis of new 1β-methylcarbapenems 1a–d bearing aminopyrimidinylthioether moiety at C-5 position of pyrrolidine ring and their antibacterial activities are described. All the compounds exhibited potent antibacterial activity. Of these carbapenems, 1d showed the best combination of antibacterial activity and stability to dehydropeptidase-I (DHP-I).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
K.S. Lee, J.H. Lim, Y.K. Kang, K.H. Yoo, D.C. Kim, K.J. Shin, D.J. Kim,