Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1397152 | European Journal of Medicinal Chemistry | 2006 | 8 Pages |
Abstract
A convenient synthesis of indolin-2-ones substituted in the 3 position by an aminomethylene group bearing different amino acid moieties is described. Their antiproliferative activities were evaluated toward a panel of human solid tumor cell lines (PC 3, DLD-1, MCF-7, M4 Beu, A549, PA 1) and healthy cell lines (a murine fibroblast L929 and a human fibroblast primary culture).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mathieu Sassatelli, Éric Debiton, Bettina Aboab, Michelle Prudhomme, Pascale Moreau,