| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1397157 | European Journal of Medicinal Chemistry | 2006 | 5 Pages |
A series of 2-aryl and 2,5-diarylfurans were synthesized and evaluated for their in vitro cytotoxicity against human cancer cells lines and on the proliferation of human peripheral blood mononuclear cells (PBMC) stimulated with phytohemaglutinin (PHA). Three compounds were found to present significant activity against the cancer cell lines without affecting the lymphocyte proliferation in PBMCs, indicating low toxicity to normal cells.
Graphical abstractA series of 2- and 2,5-arylfurans were synthesized and evaluated for their in vitro toxicity to human cancer cells lines and on the proliferation of human peripheral blood mononuclear cells (PBMC) stimulated with phytohemaglutinin (PHA).Figure optionsDownload full-size imageDownload as PowerPoint slide
