Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1397721 | European Journal of Medicinal Chemistry | 2010 | 7 Pages |
Abstract
Five new unsaturated iridolactones 3–7 related to natural cytotoxic oxylipins, Tei 9826, and iridolactone 2, were prepared by parallel synthesis from natural aucubin. It was found that perpivaloyl iridoid glucosides 2, 3, and 4 were markedly cytotoxic against both L1210 and KB-3-1 cell lines.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Vokatsoa C. Rakotondramasy, Christine Mouriès, Xavier Cachet, Abdelhak Neghra, Missam El Mourabet, François Tillequin, Michel Koch, Brigitte Deguin,