Diazinium salts with dihydroxyacetophenone skeleton: Syntheses and antimicrobial activity

Herein we report a feasible study concerning syntheses, structure and antimicrobial activity of some new diazinium salts with dihydroxyacetophenone skeleton. A fast, general, environmentally friendly, and facile method for preparation of diazinium salts under microwave and ultrasounds irradiation is presented. Antimicrobial tests prove that some diazine compounds have a remarkable activity against different microorganisms (germs and fungi), the pyrimidine derivatives being more active. Correlations between structure and antimicrobial activity are reported.

Graphical abstractSynthesis, structure and antimicrobial activity of six new diazinium salts with dihydroxyacetophenone skeleton are described.Figure optionsDownload full-size imageDownload as PowerPoint slide