| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1397981 | European Journal of Medicinal Chemistry | 2009 | 6 Pages |
Abstract
Five new type binuclear platinum(II) complexes (a-e) have been synthesized and characterized by elemental analysis, conductivity, thermal analysis, IR, UV, 1H NMR and mass spectral techniques. The cytotoxicity of the complexes was tested by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and sulforhodamine B (SRB) assays. The acute toxicity and antitumor activity of complex e in vivo were also studied.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jinchao Zhang, Lei Liu, Yuqiu Gong, Xiaoming Zheng, Mengsu Yang, Jingrong Cui, Shigang Shen,