Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1398103 | European Polymer Journal | 2014 | 5 Pages |
•2-Ketobutyric acid (2-KBA) was used as photoinitiator and emulsifier.•Multi-sensitive micelles with core and shell structure were prepared.•The micelles exhibited temperature, glucose concentration and pH sensitivity.•The work provides a new platform for development drug delivery vehicles.
The multi-sensitive micelles were prepared through a photoinitiated polymerization and self-assembly route using 2-ketobutyric acid (2-KBA) as effective water-soluble photoinitiator and emulsifier. The drug release behaviors were investigated under different glucose concentration, pH and temperature conditions. This work provides a new platform for development drug delivery vehicles with reducing possible utilization of organic solvents and initiators and surfactants.
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