Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1398175 | European Journal of Medicinal Chemistry | 2007 | 9 Pages |
Abstract
Four mixed-ligand copper(II) complexes of the nitrogen ligand bis[N-(p-tolyl)imino]acenaphthene 1 (p-Tol-BIAN). These complexes, namely [Cu(p-Tol-BIAN)2](ClO4)22, [Cu(p-Tol-BIAN)(acac)](ClO4) 3, [Cu(p-Tol-BIAN)Cl2] 4 and [Cu(p-Tol-BIAN)(AcOH)2](ClO4)25, were prepared and characterized. Solvatochromism of the novel copper complexes in various solvents has been studied. Molecular mechanics (MM+) and molecular dynamic simulations have been performed to learn more about the solvatochromic behaviour and the DNA binding affinity of these complexes.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Usama El-Ayaan, Alaa A.-M. Abdel-Aziz, Shar Al-Shihry,