| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1398716 | European Journal of Medicinal Chemistry | 2015 | 15 Pages |
Abstract
17a strongly increased the Nrf2 protein in the nucleus and enhanced ARE-driven gene transactivation, which resulted in the activation of the Nrf2-dependent cytoprotective machinery, thereby protecting cells against the carcinogen-triggered oxidative stress.
Keywords
Heme oxygenase-1ABCC3AKR1C1AKR1C2AKR1C3GCLMtert-butylhydroquinoneGCLCNQO1nuclear factor erythroid 2 p45-related factor 2HO-1Nrf2t-BHQCAPEKelch-like ECH associating protein 1NAD(P)H Quinone Oxidoreductase 1ROSt-BOOHcaffeic acid phenethyl esterCytoprotectionantioxidant responsive elementKeap 1Antioxidant activityAREtert-butyl hydroperoxideglutathione reductaseReactive oxygen species
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ken-Ming Chang, Huang-Hui Chen, Tai-Chi Wang, I-Li Chen, Yu-Tsen Chen, Shyh-Chyun Yang, Yeh-Long Chen, Hsin-Huei Chang, Chih-Hsiang Huang, Jang-Yang Chang, Chuan Shih, Ching-Chuan Kuo, Cherng-Chyi Tzeng,