Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1398998 | European Journal of Medicinal Chemistry | 2013 | 7 Pages |
Abstract
The biological potential of iridium(III) complexes of the type [Ir(η5-C5Me5)Cl2{Ph2PCH2S(O)xPh-κP}] (x = 0-2) and [Ir(η5-C5Me5)Cl{Ph2PCH2SPh-κP,κS}][PF6] even against cisplatin-resistant tumor cell lines is presented. Furthermore, structure-activity relationships and the tumoricidal action are discussed.
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Authors
Gerd Ludwig, Sanja MijatoviÄ, Ivan RanÄeloviÄ, Mirna BulatoviÄ, Djordje MiljkoviÄ, Danijela MaksimoviÄ-IvaniÄ, Marcus Korb, Heinrich Lang, Dirk Steinborn, Goran N. KaluÄeroviÄ,