Article ID Journal Published Year Pages File Type
1399157 European Journal of Medicinal Chemistry 2013 8 Pages PDF
Abstract

Liver disease is any condition that may cause liver inflammation or tissue damage and affects liver function. Natural products that are found in vegetables, fruits, plant extracts, herbs, insects, and animals, have been traditionally used for treating liver diseases. They are chemical compounds that usually have biological activities for use in drug discovery and design. Many natural products have been clinically available as potent hepatoprotective agents against commonly occurring liver diseases. This review summarizes the current progress in the basic, clinical, and translational research on natural products in treatment of various liver diseases. Furthermore, we will focus on the discovery and biological evaluation of the natural products, which shows potential as a new therapeutic agent of liver diseases.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► There are many plants have been shown to possess hepatoprotective activities. ► Natural products have now become a promising therapy for pathological liver conditions. ► Hepatoprotective potential of natural products has also been clinically evaluated.

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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