| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1399229 | European Journal of Medicinal Chemistry | 2013 | 15 Pages |
Abstract
⺠We synthesized oxazolidinone analogues bearing seven-membered heterocycle C-ring unit. ⺠Several compounds exhibited potent in vitro antibacterial activities. ⺠Compounds 21a and 21b showed high in vivo activity against MRSA. ⺠The above 21a and 21b also had promising safety profile.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Antibacterial oxazolidinone analogues having a N-hydroxyacetyl-substituted seven-membered [1,2,5]triazepane or [1,2,5]oxadiazepane C-ring unit](/preview/png/1399229.png "First Page Preview: Antibacterial oxazolidinone analogues having a N-hydroxyacetyl-substituted seven-membered [1,2,5]triazepane or [1,2,5]oxadiazepane C-ring unit")
Authors
Hideyuki Suzuki, Iwao Utsunomiya, Koichi Shudo, Norio Fukuhara, Tsutomu Iwaki, Tatsuro Yasukata,