| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1399582 | European Journal of Medicinal Chemistry | 2010 | 5 Pages |
Abstract
The synthesis and in vitro activity of R(+)-Limonene derivatives against Leishmania and Trypanosoma cruzi strains are reported. Seven compounds have shown better in vitro activity against Leishmania (V.)braziliensis than the standard drug pentamidine. Additionally, we have identified two promising new anti-T. cruzi limonene derivatives.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Cedric S. Graebin, Maria de F. Madeira, Jenicer K.U. Yokoyama-Yasunaka, Danilo C. Miguel, Silvia R.B. Uliana, Diego Benitez, Hugo Cerecetto, Mercedes González, Ricardo Gomes da Rosa, Vera Lucia Eifler-Lima,