| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1399671 | European Journal of Medicinal Chemistry | 2009 | 5 Pages |
Abstract
A series of tricyclic analogues of acyclovir and 9-{[cis-1â²,2â²-bis(hydroxymethyl)cycloprop-1â²-yl]methyl}guanine substituted in the 6 position were synthesized and screened for their activity in vitro against varicella-zoster virus (VZV) and cytomegalovirus (CMV).
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1â²,2â²-bis(hydroxymethyl)cycloprop-1â²-yl]methyl}guanine analogues](/preview/png/1399671.png "First Page Preview: Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1â²,2â²-bis(hydroxymethyl)cycloprop-1â²-yl]methyl}guanine analogues")
Authors
Tomasz Ostrowski, Bozenna Golankiewicz, Erik De Clercq, Graciela Andrei, Robert Snoeck,