| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1399678 | European Journal of Medicinal Chemistry | 2009 | 7 Pages |
Abstract
A number of 1-propargyl-1,8-naphthyridine-3-carboxamide derivatives (15–35) have been synthesized and screened for their in vitro cytotoxicity and anti-inflammatory activity. Compounds 22, 31 and 34 have shown high cytotoxicity against a number of cancer cell lines, while compound 24 showed significant anti-inflammatory activity.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Vivek Kumar, Manu Jaggi, Anu T. Singh, Alka Madaan, Vinod Sanna, Pratibha Singh, Pramod K. Sharma, Raghuveer Irchhaiya, Anand C. Burman,