Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1399703 | European Journal of Medicinal Chemistry | 2008 | 6 Pages |
Abstract
Novel 1-aryl-3-(5-nitro-2-thienyl)-4-aroyl-pyrazoles 7 have been synthesized by the 1,3-dipolar cycloaddition of 3-arylsydnones 3 with 1-aryl-3-(5-nitro-2-thienyl)-2-propyn-1-ones 6. The newly synthesized compounds were well characterized by elemental analysis, IR, 1H NMR and mass spectral studies. They were also screened for their antibacterial and antifungal activities against a variety of microorganisms and the results of such studies have been discussed in this article.
Graphical abstractNovel 1-aryl-4-aroyl-3-(5-nitro-2-thienyl) pyrazoles have been synthesized by the 1,3-dipolar cycloaddition of 3-arylsydnones with 1-aryl-3-(5-nitro-2-thienyl)-2-propyne-1-ones.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
N. Satheesha Rai, Balakrishna Kalluraya, B. Lingappa, Shaliny Shenoy, Vedavati G. Puranic,