Article ID Journal Published Year Pages File Type
1399712 European Journal of Medicinal Chemistry 2008 4 Pages PDF
Abstract

Homoclausenamide was synthesized for the first time, and the intramolecular cyclization study of N-methyl-3-phenyl-N-(2-(E)-phenylethenyl)-trans(cis)-oxiranecarboxamide well demonstrated how the stereochemistry affects the cyclization paths.

Graphical abstractUnder Lewis acid condition, compound 8 undergoes cyclizations to give Homoclausenamide and Dehydroclausenamide.Figure optionsDownload full-size imageDownload as PowerPoint slide

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Physical Sciences and Engineering Chemistry Organic Chemistry
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