Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1399870 | European Journal of Medicinal Chemistry | 2008 | 8 Pages |
Abstract
QSAR studies have been performed on some PPAR-γ agonist thiazolidinediones to identify the essential structural and physico-chemical features for their agonistic activity. The predicted activities by the developed models were in good accordance with the observed activities. The developed QSAR model was validated using a test set of five compounds and good predictive r2 values of generated equations confirm the robustness of the model
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Authors
Anshuman Dixit, Anil K. Saxena,