Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1399916 | European Journal of Medicinal Chemistry | 2007 | 7 Pages |
Abstract
A series of novel fluorocyclopropyl nucleosides were synthesized starting from acetol using the Simmons–Smith reaction as a key reaction. All the nucleosides synthesized were assayed against several viruses. Among the compounds synthesized, the uracil analogue 22 showed moderate anti-HCMV activity (10.61 μg/mL, in AD-169).
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Aihong Kim, Joon Hee Hong,