| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1399949 | European Journal of Medicinal Chemistry | 2007 | 7 Pages |
Abstract
In the search for new chemotherapeutic agents useful against Rubella virus (RV) infections, a solution-phase parallel approach for the synthesis of a small library of 4-alkylamino-6-(2-hydroxyethyl)-2-methylthiopyrimidines has been set up, based on previous results from our research group. Biological evaluation of the newly synthesized compounds pointed out their interesting properties as anti-RV agents with IC50 values in the micromolar range.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Claudia Mugnaini, Elena Petricci, Maurizio Botta, Federico Corelli, Paola Mastromarino, Gianluca Giorgi,